DIMENSIONSWheelbase: 101.2 inLength: 163.0 inWidth: 70.9 in Height: 63.5 inPassenger volume: 97 cu ftCargo volume: 24 cu ftCurb weight: 3205 lb
258. Everyone from whom this Panel heard (except Ensor and Geffen) made it clear that the intermingling of professional and personal boundaries within and between those working for Equal Education arose out of a deep commitment to the work of the organization, the nature of the work involved, the challenges facing the organisation on all fronts and that it was often difficult to separate private lives from EE responsibilities.
To evaluate the biological significance of hybrids in humans, we first determined whether hybrids between blood cells and epithelial-derived cancer cells were detectible. To accomplish this, we exploited a disease scenario that supports identification of hybrids harboring properties of peripheral mononuclear blood cells and epithelial cells (30)—specifically, the analysis of tumor biopsies from female cancer patients who had previously received a sex-mismatched bone marrow transplant and subsequently developed a secondary solid tumor. In these patients, only the male donor–transplanted hematopoietic cells should contain a Y chromosome; therefore, identification of Y chromosome–positive nuclei in cytokeratin-positive cells within the tumor biopsy could indicate fusion between a peripheral mononuclear blood cell and an epithelial tumor cell. We identified tumor epithelia by a pathologic review of H&E-stained tumor biopsies, and then we probed tissue sections with pan-cytokeratin antibodies and interrogated with Y chromosome FISH probes to identify cellular products consistent with fusion between neoplastic cells and transplanted male hematopoietic cells (Fig. 5 and fig. S9). In a biopsy from a female patient with pancreatic ductal adenocarcinoma (PDAC), neoplastic cell nuclei containing a Y chromosome were detectible throughout regions of the tumor (Fig. 5, A to E, and fig. S9, A and B), as well as in premalignant regions of pancreatic intraepithelial neoplasia (PanIN; fig. S9C). Confocal microscopy confirmed that Y chromosomes were located in nuclei of cytokeratin-positive epithelial tumor cells (see higher magnifications in Fig. 5). For these studies, tumor specimens from seven patients were examined, and all contained evidence of fusion by these criteria. Y chromosome–positive epithelial tumor cells were not unique to PDAC, as fusion hybrids were detected in other solid tumors from female recipients of sex-mismatched transplantation, including renal cell carcinoma, head and neck squamous cell carcinoma, and lung adenocarcinoma (fig. S9, D to F). Control tissue staining from female and male tissue samples were carried as controls for Y chromosome detection (fig. S10, A and B). These observations were consistent with previous case reports of cell fusion in human cancer using a variety of other detection methods (11, 17, 31, 32).
215. The first draft of the Report of the Human Resources Subcommittee was considered on the day of the hearing, 11th June and was subsequently amended.83
“As we continue to create differentiated shopping experiences across our networks, websites, apps and social pages, our private label credit card program with Synchrony will help us deliver compelling value and choice to consumers,” Miller added.
266. Sixth, there is nothing unusual in providing for an internal preliminary investigation or two-stage process as did the Equal Education Disciplinary Code. All organisations of whatever staffing capacity have such internal investigations or hearings where investigators or adjudicators know the persons making complaints, those who face the complaints and those who attempt to prove or disprove the complaints. That is usually the role of a Human Resources department.
“I mean, I saw you at the trial. You took on the government, and I thought you did very well. You could be downtown with a big firm as a trial partner.”
The test is used with blood specimens, including capillary “fingerstick” whole blood, from individuals with signs and symptoms of Ebola virus disease (EVD) in addition to other risk factors, such as living in an area with large numbers of EVD cases and/or having contact with other individuals exhibiting signs and symptoms of EVD.
… In the best cases, consultants can offer experienced, impartial analysis and recommendations for government action.
“What the fundamental principles of justice are which underlie our system of law, …. have never been exhaustively defeined and are not altogether clear. In Russell v Duke of Norfolk and Others (1949) 1 All E.R. 109, Lord Tucker said at p 118 that –
A team of researchers based at The University of Manchester have found a low cost method for producing graphene printed electronics, which significantly speeds up and reduces the cost of conductive graphene inks.
Certainly, Premier Alden McLaughlin is under no obligation to maintain the FCO’s brand of silence …. Remember, the governor and the FCO work for the Queen, but the premier and our MLAs work for the people of Cayman.
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